.PrlrAntibodyComparison-module__kLsYyW__root{--prlr-bg:#f6f8f6;--prlr-panel:#ffffffeb;--prlr-panel-solid:#fff;--prlr-ink:#17201d;--prlr-muted:#5c6964;--prlr-soft:#7a8782;--prlr-line:#dce4e0;--prlr-line-strong:#c5d1cc;--prlr-green:#287962;--prlr-green-soft:#e6f3ee;--prlr-blue:#3b65a7;--prlr-blue-soft:#e9eff9;--prlr-amber:#a76616;--prlr-amber-soft:#fff2da;--prlr-red:#a04942;--prlr-red-soft:#fbeae7;--prlr-membrane-a:#b8d9cd;--prlr-membrane-b:#c8d7e7;border:1px solid var(--prlr-line-strong);color:var(--prlr-ink);background:radial-gradient(circle at 92% 0%, #3b65a717, transparent 27rem), radial-gradient(circle at 2% 5%, #2879621a, transparent 24rem), var(--prlr-bg);font-family:var(--font-geist-sans), Arial, sans-serif;border-radius:clamp(1.1rem,3vw,1.75rem);margin:clamp(2.25rem,5vw,4.75rem) 0;position:relative;overflow:hidden;box-shadow:0 26px 70px #192c251c}.dark .PrlrAntibodyComparison-module__kLsYyW__root{--prlr-bg:#111714;--prlr-panel:#19221eed;--prlr-panel-solid:#19221e;--prlr-ink:#edf4f0;--prlr-muted:#afbbb5;--prlr-soft:#8c9a93;--prlr-line:#2d3934;--prlr-line-strong:#405048;--prlr-green:#73c9ac;--prlr-green-soft:#19392f;--prlr-blue:#8caee5;--prlr-blue-soft:#1f304c;--prlr-amber:#e2b466;--prlr-amber-soft:#443317;--prlr-red:#e2938b;--prlr-red-soft:#482724;--prlr-membrane-a:#31584a;--prlr-membrane-b:#304762;box-shadow:0 30px 80px #00000057}.PrlrAntibodyComparison-module__kLsYyW__header{border-bottom:1px solid var(--prlr-line);grid-template-columns:minmax(0,1fr) minmax(15rem,.45fr);align-items:end;gap:2rem;padding:clamp(1.45rem,4vw,2.75rem);display:grid}.PrlrAntibodyComparison-module__kLsYyW__eyebrow,.PrlrAntibodyComparison-module__kLsYyW__kicker,.PrlrAntibodyComparison-module__kLsYyW__filterLabel{color:var(--prlr-green);letter-spacing:.13em;text-transform:uppercase;font-size:.68rem;font-weight:780;line-height:1.3;display:block}.PrlrAntibodyComparison-module__kLsYyW__header h2{letter-spacing:-.045em;max-width:42rem;margin:.65rem 0 0;font-size:clamp(1.75rem,4vw,3.15rem);font-weight:710;line-height:1}.PrlrAntibodyComparison-module__kLsYyW__header p{max-width:46rem;color:var(--prlr-muted);margin:1rem 0 0;font-size:clamp(.92rem,1.3vw,1.05rem);line-height:1.65}.PrlrAntibodyComparison-module__kLsYyW__legend,.PrlrAntibodyComparison-module__kLsYyW__badges{flex-wrap:wrap;gap:.38rem;display:flex}.PrlrAntibodyComparison-module__kLsYyW__legend{place-content:flex-end}.PrlrAntibodyComparison-module__kLsYyW__badge{width:-moz-fit-content;width:fit-content;min-height:1.42rem;color:var(--prlr-green);background:var(--prlr-green-soft);font-family:var(--font-geist-mono), Consolas, monospace;letter-spacing:.035em;text-transform:uppercase;border:1px solid;border-radius:999px;align-items:center;padding:.18rem .46rem;font-size:.57rem;font-weight:740;line-height:1.1;display:inline-flex}.PrlrAntibodyComparison-module__kLsYyW__badge[data-kind=reported]{color:var(--prlr-blue);background:var(--prlr-blue-soft)}.PrlrAntibodyComparison-module__kLsYyW__badge[data-kind=modeled]{color:var(--prlr-amber);background:var(--prlr-amber-soft)}.PrlrAntibodyComparison-module__kLsYyW__badge[data-kind=alleged]{color:var(--prlr-red);background:var(--prlr-red-soft)}.PrlrAntibodyComparison-module__kLsYyW__mechanism{border-bottom:1px solid var(--prlr-line);background:var(--prlr-panel);grid-template-columns:minmax(13rem,.72fr) minmax(20rem,1.45fr);align-items:center;gap:clamp(1rem,3vw,2.5rem);padding:clamp(1.25rem,4vw,2.5rem);display:grid}.PrlrAntibodyComparison-module__kLsYyW__mechanismCopy h3{letter-spacing:-.025em;margin:.55rem 0 0;font-size:clamp(1.2rem,2.2vw,1.65rem);font-weight:700;line-height:1.15}.PrlrAntibodyComparison-module__kLsYyW__mechanismCopy p{color:var(--prlr-muted);margin:.7rem 0 0;font-size:.82rem;line-height:1.6}.PrlrAntibodyComparison-module__kLsYyW__controls{flex-wrap:wrap;gap:.5rem;margin-top:1.1rem;display:flex}.PrlrAntibodyComparison-module__kLsYyW__controls button{border:1px solid var(--prlr-line-strong);min-height:2.35rem;color:var(--prlr-ink);background:var(--prlr-panel-solid);font:inherit;cursor:pointer;border-radius:.55rem;align-items:center;gap:.42rem;padding:.42rem .72rem;font-size:.72rem;font-weight:700;transition:border-color .15s,color .15s,transform .15s;display:inline-flex}.PrlrAntibodyComparison-module__kLsYyW__controls button:hover{border-color:var(--prlr-green);color:var(--prlr-green);transform:translateY(-1px)}.PrlrAntibodyComparison-module__kLsYyW__controls svg{width:.9rem;height:.9rem}.PrlrAntibodyComparison-module__kLsYyW__mechanismStage{border:1px solid var(--prlr-line);background:linear-gradient(180deg, #3b65a70d, transparent 52%), var(--prlr-panel-solid);border-radius:1.2rem;min-height:15rem;position:relative;overflow:hidden}.PrlrAntibodyComparison-module__kLsYyW__mechanismStage:after{border-radius:inherit;content:"";pointer-events:none;position:absolute;inset:0;box-shadow:inset 0 1px #ffffff73}.PrlrAntibodyComparison-module__kLsYyW__mechanismStage svg{width:100%;height:auto;min-height:15rem;display:block}.PrlrAntibodyComparison-module__kLsYyW__membrane{opacity:.8}.PrlrAntibodyComparison-module__kLsYyW__receptor{fill:none;stroke:var(--prlr-green);stroke-linecap:round;stroke-linejoin:round;stroke-width:8px}.PrlrAntibodyComparison-module__kLsYyW__antibody{fill:none;stroke:var(--prlr-blue);stroke-linecap:round;stroke-linejoin:round;stroke-width:6px}.PrlrAntibodyComparison-module__kLsYyW__antibody circle{fill:var(--prlr-blue-soft)}.PrlrAntibodyComparison-module__kLsYyW__antibodyLeft{animation:4.8s cubic-bezier(.45,0,.2,1) infinite PrlrAntibodyComparison-module__kLsYyW__bindLeft}.PrlrAntibodyComparison-module__kLsYyW__antibodyRight{animation:4.8s cubic-bezier(.45,0,.2,1) .65s infinite PrlrAntibodyComparison-module__kLsYyW__bindRight}.PrlrAntibodyComparison-module__kLsYyW__ligand{fill:var(--prlr-amber-soft);stroke:var(--prlr-amber);stroke-linecap:round;stroke-width:4px;animation:4.8s ease-in-out infinite PrlrAntibodyComparison-module__kLsYyW__ligandApproach}.PrlrAntibodyComparison-module__kLsYyW__signalPath{fill:none;stroke:var(--prlr-line-strong);stroke-dasharray:5 8;stroke-width:2px}.PrlrAntibodyComparison-module__kLsYyW__signalPulse{fill:var(--prlr-green);animation:4.8s ease-in-out infinite PrlrAntibodyComparison-module__kLsYyW__signalFade}.PrlrAntibodyComparison-module__kLsYyW__isPaused *,.PrlrAntibodyComparison-module__kLsYyW__isPaused:before,.PrlrAntibodyComparison-module__kLsYyW__isPaused:after{animation-play-state:paused!important}.PrlrAntibodyComparison-module__kLsYyW__stageLabel{z-index:2;color:var(--prlr-soft);font-family:var(--font-geist-mono), Consolas, monospace;letter-spacing:.06em;text-transform:uppercase;font-size:clamp(.5rem,1.1vw,.62rem);font-weight:720;line-height:1;position:absolute}.PrlrAntibodyComparison-module__kLsYyW__stageLabel[data-position=top]{top:.72rem;left:50%;transform:translate(-50%)}.PrlrAntibodyComparison-module__kLsYyW__stageLabel[data-position=receptor]{top:6.7rem;left:50%;transform:translate(-50%)}.PrlrAntibodyComparison-module__kLsYyW__stageLabel[data-position=left]{color:var(--prlr-blue);top:4.1rem;left:7%}.PrlrAntibodyComparison-module__kLsYyW__stageLabel[data-position=right]{color:var(--prlr-blue);top:4.1rem;right:7%}.PrlrAntibodyComparison-module__kLsYyW__stageLabel[data-position=bottom]{bottom:.7rem;right:1rem}.PrlrAntibodyComparison-module__kLsYyW__filterBar{border-bottom:1px solid var(--prlr-line);justify-content:space-between;align-items:center;gap:1rem;padding:1rem clamp(1.25rem,4vw,2.5rem);display:flex}.PrlrAntibodyComparison-module__kLsYyW__filterHint{color:var(--prlr-soft);margin-top:.22rem;font-size:.68rem;display:block}.PrlrAntibodyComparison-module__kLsYyW__tabsScroller{scrollbar-width:thin;min-width:0;overflow-x:auto}.PrlrAntibodyComparison-module__kLsYyW__tabs{border:1px solid var(--prlr-line);background:var(--prlr-panel);border-radius:.72rem;width:max-content;padding:.25rem;display:flex}.PrlrAntibodyComparison-module__kLsYyW__tabs button{min-height:2.1rem;color:var(--prlr-muted);font:inherit;white-space:nowrap;cursor:pointer;background:0 0;border:0;border-radius:.5rem;padding:.36rem .68rem;font-size:.67rem;font-weight:700;transition:color .14s,background .14s,box-shadow .14s}.PrlrAntibodyComparison-module__kLsYyW__tabs button:hover{color:var(--prlr-ink)}.PrlrAntibodyComparison-module__kLsYyW__tabs button[aria-selected=true]{color:var(--prlr-panel-solid);background:var(--prlr-ink);box-shadow:0 3px 12px #12211b29}.dark .PrlrAntibodyComparison-module__kLsYyW__tabs button[aria-selected=true]{color:#101713;background:#edf4f0}.PrlrAntibodyComparison-module__kLsYyW__liveStatus{border-bottom:1px solid var(--prlr-line);color:var(--prlr-soft);background:var(--prlr-panel);font-family:var(--font-geist-mono), Consolas, monospace;margin:0;padding:.55rem clamp(1.25rem,4vw,2.5rem);font-size:.62rem}.PrlrAntibodyComparison-module__kLsYyW__comparisonPanel{background:var(--prlr-panel)}.PrlrAntibodyComparison-module__kLsYyW__tableWrap{width:100%;overflow-x:auto}.PrlrAntibodyComparison-module__kLsYyW__table{border-collapse:collapse;table-layout:fixed;width:100%;min-width:47rem}.PrlrAntibodyComparison-module__kLsYyW__table th,.PrlrAntibodyComparison-module__kLsYyW__table td{border-right:1px solid var(--prlr-line);border-bottom:1px solid var(--prlr-line);text-align:left;vertical-align:top;padding:1.15rem clamp(.8rem,2vw,1.4rem)}.PrlrAntibodyComparison-module__kLsYyW__table tr>:last-child{border-right:0}.PrlrAntibodyComparison-module__kLsYyW__table thead th{color:var(--prlr-soft);background:color-mix(in srgb, var(--prlr-bg) 70%, transparent);letter-spacing:.09em;text-transform:uppercase;font-size:.66rem;font-weight:780}.PrlrAntibodyComparison-module__kLsYyW__table thead th:first-child{width:23%}.PrlrAntibodyComparison-module__kLsYyW__table thead span,.PrlrAntibodyComparison-module__kLsYyW__table thead small{display:block}.PrlrAntibodyComparison-module__kLsYyW__table thead span{color:var(--prlr-ink);font-size:.78rem}.PrlrAntibodyComparison-module__kLsYyW__table thead small{letter-spacing:.04em;text-transform:none;margin-top:.22rem;font-size:.58rem;font-weight:620}.PrlrAntibodyComparison-module__kLsYyW__table tbody th>span,.PrlrAntibodyComparison-module__kLsYyW__table tbody th>small{display:block}.PrlrAntibodyComparison-module__kLsYyW__table tbody th>span{color:var(--prlr-green);font-family:var(--font-geist-mono), Consolas, monospace;letter-spacing:.075em;text-transform:uppercase;font-size:.64rem;font-weight:760}.PrlrAntibodyComparison-module__kLsYyW__table tbody th>small{color:var(--prlr-ink);margin-top:.4rem;font-size:.78rem;font-weight:680;line-height:1.35}.PrlrAntibodyComparison-module__kLsYyW__table tbody tr:hover{background:color-mix(in srgb, var(--prlr-green-soft) 35%, transparent)}.PrlrAntibodyComparison-module__kLsYyW__evidenceList{gap:.95rem;margin:0;padding:0;list-style:none;display:grid}.PrlrAntibodyComparison-module__kLsYyW__evidenceList li{margin:0;padding:0}.PrlrAntibodyComparison-module__kLsYyW__evidenceList p{color:var(--prlr-ink);margin:0;font-size:.77rem;line-height:1.55}.PrlrAntibodyComparison-module__kLsYyW__badges{margin-top:.48rem}.PrlrAntibodyComparison-module__kLsYyW__noMatch{color:var(--prlr-soft);font-size:.72rem;font-style:italic}.PrlrAntibodyComparison-module__kLsYyW__cards{display:none}.PrlrAntibodyComparison-module__kLsYyW__bottomLine{color:#f5faf7;background:#17231e;grid-template-columns:auto minmax(0,1fr);align-items:start;gap:1rem;padding:clamp(1.3rem,4vw,2.3rem);display:grid}.PrlrAntibodyComparison-module__kLsYyW__bottomLine>span{color:#9ed0bf;width:2.3rem;height:2.3rem;font-family:var(--font-geist-mono), Consolas, monospace;border:1px solid #ffffff40;border-radius:50%;place-items:center;font-size:.64rem;display:grid}.PrlrAntibodyComparison-module__kLsYyW__bottomLine strong{color:#9ed0bf;letter-spacing:.12em;text-transform:uppercase;font-size:.68rem;display:block}.PrlrAntibodyComparison-module__kLsYyW__bottomLine p{color:#f5faf7;max-width:53rem;margin:.45rem 0 0;font-size:clamp(.92rem,1.45vw,1.08rem);font-weight:570;line-height:1.55}.PrlrAntibodyComparison-module__kLsYyW__tabs button:focus-visible,.PrlrAntibodyComparison-module__kLsYyW__controls button:focus-visible{outline:3px solid color-mix(in srgb, var(--prlr-blue) 70%, transparent);outline-offset:3px}.PrlrAntibodyComparison-module__kLsYyW__srOnly{clip:rect(0, 0, 0, 0);white-space:nowrap;border:0;width:1px;height:1px;margin:-1px;padding:0;position:absolute;overflow:hidden}@keyframes PrlrAntibodyComparison-module__kLsYyW__bindLeft{0%,16%{opacity:.3;transform:translate(80px,38px)rotate(-20deg)}42%,78%{opacity:1;transform:translate(300px,66px)rotate(38deg)}to{opacity:.3;transform:translate(80px,38px)rotate(-20deg)}}@keyframes PrlrAntibodyComparison-module__kLsYyW__bindRight{0%,16%{opacity:.3;transform:translate(604px,38px)rotate(20deg)}42%,78%{opacity:1;transform:translate(384px,66px)rotate(-38deg)}to{opacity:.3;transform:translate(604px,38px)rotate(20deg)}}@keyframes PrlrAntibodyComparison-module__kLsYyW__ligandApproach{0%,15%{opacity:1;transform:translateY(-17px)}38%,78%{opacity:.35;transform:translateY(10px)}to{opacity:1;transform:translateY(-17px)}}@keyframes PrlrAntibodyComparison-module__kLsYyW__signalFade{0%,22%{opacity:1;transform:translateY(0)}45%,78%{opacity:.15;transform:translateY(5px)}to{opacity:1;transform:translateY(0)}}@media (max-width:900px){.PrlrAntibodyComparison-module__kLsYyW__header{grid-template-columns:1fr;gap:1.2rem}.PrlrAntibodyComparison-module__kLsYyW__legend{justify-content:flex-start}.PrlrAntibodyComparison-module__kLsYyW__mechanism{grid-template-columns:1fr}}@media (max-width:680px){.PrlrAntibodyComparison-module__kLsYyW__root{border-radius:1rem;margin-left:-.55rem;margin-right:-.55rem}.PrlrAntibodyComparison-module__kLsYyW__header,.PrlrAntibodyComparison-module__kLsYyW__mechanism{padding:1.25rem}.PrlrAntibodyComparison-module__kLsYyW__mechanismStage{min-height:11.5rem}.PrlrAntibodyComparison-module__kLsYyW__mechanismStage svg{min-height:11.5rem;transform:scale(1.08)}.PrlrAntibodyComparison-module__kLsYyW__stageLabel[data-position=receptor]{top:5.1rem}.PrlrAntibodyComparison-module__kLsYyW__stageLabel[data-position=left]{top:3.1rem;left:4%}.PrlrAntibodyComparison-module__kLsYyW__stageLabel[data-position=right]{top:3.1rem;right:4%}.PrlrAntibodyComparison-module__kLsYyW__filterBar{padding:.95rem 1.25rem;display:block}.PrlrAntibodyComparison-module__kLsYyW__tabsScroller{margin-top:.8rem;padding-bottom:.18rem}.PrlrAntibodyComparison-module__kLsYyW__liveStatus{padding-left:1.25rem;padding-right:1.25rem}.PrlrAntibodyComparison-module__kLsYyW__tableWrap{display:none}.PrlrAntibodyComparison-module__kLsYyW__cards{display:grid}.PrlrAntibodyComparison-module__kLsYyW__card{border-bottom:1px solid var(--prlr-line)}.PrlrAntibodyComparison-module__kLsYyW__card>header{background:color-mix(in srgb, var(--prlr-bg) 75%, transparent);padding:1rem 1.25rem}.PrlrAntibodyComparison-module__kLsYyW__card>header>span{color:var(--prlr-green);font-family:var(--font-geist-mono), Consolas, monospace;letter-spacing:.08em;text-transform:uppercase;font-size:.6rem;font-weight:760;display:block}.PrlrAntibodyComparison-module__kLsYyW__card>header h3{letter-spacing:-.015em;margin:.35rem 0 0;font-size:.91rem;font-weight:690}.PrlrAntibodyComparison-module__kLsYyW__cardCandidate{border-top:1px solid var(--prlr-line);padding:1rem 1.25rem 1.15rem}.PrlrAntibodyComparison-module__kLsYyW__cardCandidate h4{color:var(--prlr-ink);align-items:baseline;gap:.45rem;margin:0 0 .8rem;font-size:.82rem;font-weight:780;display:flex}.PrlrAntibodyComparison-module__kLsYyW__cardCandidate h4 small{color:var(--prlr-soft);font-size:.62rem;font-weight:620}.PrlrAntibodyComparison-module__kLsYyW__evidenceList p{font-size:.8rem}}@media (prefers-reduced-motion:reduce){.PrlrAntibodyComparison-module__kLsYyW__root *,.PrlrAntibodyComparison-module__kLsYyW__root :before,.PrlrAntibodyComparison-module__kLsYyW__root :after{scroll-behavior:auto!important;transition-duration:.001ms!important;animation-duration:.001ms!important;animation-iteration-count:1!important}.PrlrAntibodyComparison-module__kLsYyW__antibodyLeft{opacity:1;transform:translate(300px,66px)rotate(38deg)}.PrlrAntibodyComparison-module__kLsYyW__antibodyRight{opacity:1;transform:translate(384px,66px)rotate(-38deg)}.PrlrAntibodyComparison-module__kLsYyW__ligand{opacity:.35;transform:translateY(10px)}.PrlrAntibodyComparison-module__kLsYyW__signalPulse{opacity:.15}}
.MpcPathwayExplorer-module__EJMKZq__root{--mpc-surface:var(--tl-panel-solid,#fdfefb);--mpc-surface-muted:var(--tl-panel-muted,#eef2ed);--mpc-canvas:var(--tl-canvas-raised,#f8f9f6);--mpc-ink:var(--tl-ink,#17211f);--mpc-ink-soft:var(--tl-ink-soft,#42504c);--mpc-muted:var(--tl-ink-muted,#606d69);--mpc-faint:var(--tl-ink-faint,#8b9692);--mpc-line:var(--tl-line,#1b312b1f);--mpc-line-strong:var(--tl-line-strong,#1b312b33);--mpc-blue:var(--tl-brand,#315fce);--mpc-blue-soft:var(--tl-brand-soft,#e7edfc);--mpc-green:var(--tl-eucalyptus,#2f7868);--mpc-green-soft:var(--tl-eucalyptus-soft,#dfece7);--mpc-amber:#9b651d;--mpc-amber-soft:#fff1d8;--mpc-red:#a34b45;--mpc-red-soft:#fbe9e6;border:1px solid var(--mpc-line-strong);color:var(--mpc-ink);background:radial-gradient(circle at 100% 0%, color-mix(in srgb, var(--mpc-blue) 10%, transparent), transparent 29rem), radial-gradient(circle at 0% 20%, color-mix(in srgb, var(--mpc-green) 9%, transparent), transparent 27rem), var(--mpc-canvas);box-shadow:var(--tl-shadow-md,0 24px 65px #14231f1f);font-family:var(--font-geist-sans), var(--font-inter), Arial, sans-serif;border-radius:clamp(1.15rem,3vw,1.8rem);margin:clamp(2.5rem,6vw,5rem) 0;position:relative;overflow:hidden}.dark .MpcPathwayExplorer-module__EJMKZq__root{--mpc-amber:#e2b365;--mpc-amber-soft:#3e301a;--mpc-red:#e18d86;--mpc-red-soft:#432725}.MpcPathwayExplorer-module__EJMKZq__header{border-bottom:1px solid var(--mpc-line);grid-template-columns:minmax(0,1fr) minmax(13rem,.4fr);align-items:end;gap:1.5rem 2rem;padding:clamp(1.4rem,4vw,2.5rem);display:grid}.MpcPathwayExplorer-module__EJMKZq__headingCopy{min-width:0}.MpcPathwayExplorer-module__EJMKZq__eyebrow,.MpcPathwayExplorer-module__EJMKZq__toolbarLabel,.MpcPathwayExplorer-module__EJMKZq__activeExplanation>span{color:var(--mpc-green);letter-spacing:.13em;text-transform:uppercase;align-items:center;gap:.42rem;font-size:.66rem;font-weight:780;line-height:1.35;display:flex}.MpcPathwayExplorer-module__EJMKZq__eyebrow svg{width:.9rem;height:.9rem}.MpcPathwayExplorer-module__EJMKZq__header h3,.MpcPathwayExplorer-module__EJMKZq__comparisonHeading h3{max-width:42rem;color:var(--mpc-ink);letter-spacing:-.045em;text-wrap:balance;margin:.7rem 0 0;font-size:clamp(1.65rem,4vw,2.75rem);font-weight:720;line-height:1.02}.MpcPathwayExplorer-module__EJMKZq__header p,.MpcPathwayExplorer-module__EJMKZq__comparisonHeading p{max-width:46rem;color:var(--mpc-muted);margin:.95rem 0 0;font-size:.92rem;line-height:1.68}.MpcPathwayExplorer-module__EJMKZq__legend,.MpcPathwayExplorer-module__EJMKZq__activeBadges,.MpcPathwayExplorer-module__EJMKZq__cardBadges,.MpcPathwayExplorer-module__EJMKZq__tableBadges{flex-wrap:wrap;gap:.38rem;display:flex}.MpcPathwayExplorer-module__EJMKZq__legend{place-content:flex-end}.MpcPathwayExplorer-module__EJMKZq__badge{width:-moz-fit-content;width:fit-content;min-height:1.45rem;color:var(--mpc-green);background:var(--mpc-green-soft);font-family:var(--font-geist-mono), Consolas, monospace;letter-spacing:.035em;text-transform:uppercase;border:1px solid;border-radius:999px;align-items:center;padding:.18rem .48rem;font-size:.56rem;font-weight:760;line-height:1.15;display:inline-flex}.MpcPathwayExplorer-module__EJMKZq__badge[data-kind=preclinical]{color:var(--mpc-amber);background:var(--mpc-amber-soft)}.MpcPathwayExplorer-module__EJMKZq__badge[data-kind=hypothesis]{color:var(--mpc-blue);background:var(--mpc-blue-soft)}.MpcPathwayExplorer-module__EJMKZq__conceptNotice{border:1px solid color-mix(in srgb, var(--mpc-amber) 48%, transparent);color:var(--mpc-ink-soft);background:var(--mpc-amber-soft);border-radius:.85rem;align-items:flex-start;gap:.72rem;margin:clamp(1rem,3vw,1.5rem) clamp(1.25rem,4vw,2.5rem) 0;padding:.85rem 1rem;display:flex}.MpcPathwayExplorer-module__EJMKZq__conceptNotice svg{width:1rem;height:1rem;color:var(--mpc-amber);flex:none;margin-top:.14rem}.MpcPathwayExplorer-module__EJMKZq__conceptNotice p{margin:0;font-size:.75rem;line-height:1.55}.MpcPathwayExplorer-module__EJMKZq__conceptNotice strong{color:var(--mpc-ink)}.MpcPathwayExplorer-module__EJMKZq__toolbar{justify-content:space-between;align-items:center;gap:1rem;padding:1.35rem clamp(1.25rem,4vw,2.5rem) .8rem;display:flex}.MpcPathwayExplorer-module__EJMKZq__toolbarHint{color:var(--mpc-faint);margin-top:.2rem;font-size:.64rem;display:block}.MpcPathwayExplorer-module__EJMKZq__motionControls{flex-wrap:wrap;justify-content:flex-end;gap:.45rem;display:flex}.MpcPathwayExplorer-module__EJMKZq__motionControls button{border:1px solid var(--mpc-line-strong);min-height:2.45rem;color:var(--mpc-ink-soft);background:var(--mpc-surface);border-radius:.7rem;justify-content:center;align-items:center;gap:.42rem;padding:.55rem .78rem;font-size:.68rem;font-weight:730;transition:border-color .15s,color .15s,background .15s,transform .15s;display:inline-flex}.MpcPathwayExplorer-module__EJMKZq__motionControls button:hover:not(:disabled){border-color:var(--mpc-blue);color:var(--mpc-blue);background:var(--mpc-blue-soft);transform:translateY(-1px)}.MpcPathwayExplorer-module__EJMKZq__motionControls button:disabled{cursor:not-allowed;opacity:.65}.MpcPathwayExplorer-module__EJMKZq__motionControls svg{width:.88rem;height:.88rem}.MpcPathwayExplorer-module__EJMKZq__tabsScroller{scrollbar-width:thin;padding:0 clamp(1.25rem,4vw,2.5rem) .45rem;overflow-x:auto}.MpcPathwayExplorer-module__EJMKZq__tabs{grid-template-columns:repeat(3,minmax(10rem,1fr));gap:.45rem;min-width:33rem;display:grid}.MpcPathwayExplorer-module__EJMKZq__tabs button{border:1px solid var(--mpc-line);min-height:3rem;color:var(--mpc-muted);background:color-mix(in srgb, var(--mpc-surface) 78%, transparent);text-align:left;border-radius:.75rem;align-items:center;gap:.62rem;padding:.62rem .78rem;font-size:.72rem;font-weight:720;transition:border-color .15s,color .15s,background .15s;display:flex}.MpcPathwayExplorer-module__EJMKZq__tabs button>span{color:var(--mpc-faint);font-family:var(--font-geist-mono), Consolas, monospace;font-size:.58rem}.MpcPathwayExplorer-module__EJMKZq__tabs button:hover{color:var(--mpc-ink);border-color:var(--mpc-line-strong)}.MpcPathwayExplorer-module__EJMKZq__tabs button[aria-selected=true]{color:var(--mpc-ink);border-color:var(--mpc-blue);background:var(--mpc-blue-soft);box-shadow:inset 0 -2px 0 var(--mpc-blue)}.MpcPathwayExplorer-module__EJMKZq__tabs button[aria-selected=true]>span{color:var(--mpc-blue)}.MpcPathwayExplorer-module__EJMKZq__motionControls button:focus-visible,.MpcPathwayExplorer-module__EJMKZq__tabs button:focus-visible{outline:3px solid color-mix(in srgb, var(--mpc-blue) 42%, transparent);outline-offset:2px}.MpcPathwayExplorer-module__EJMKZq__liveStatus,.MpcPathwayExplorer-module__EJMKZq__srOnly{clip:rect(0, 0, 0, 0);white-space:nowrap;border:0;width:1px;height:1px;margin:-1px;padding:0;position:absolute;overflow:hidden}.MpcPathwayExplorer-module__EJMKZq__pathwayPanel{grid-template-columns:minmax(15rem,.7fr) minmax(0,1.3fr);gap:1rem;padding:.85rem clamp(1.25rem,4vw,2.5rem) clamp(1.5rem,4vw,2.5rem);display:grid}.MpcPathwayExplorer-module__EJMKZq__activeExplanation,.MpcPathwayExplorer-module__EJMKZq__mechanismStage{border:1px solid var(--mpc-line);background:var(--mpc-surface);border-radius:1rem}.MpcPathwayExplorer-module__EJMKZq__activeExplanation{flex-direction:column;min-width:0;padding:clamp(1.1rem,3vw,1.6rem);display:flex}.MpcPathwayExplorer-module__EJMKZq__activeExplanation h4{color:var(--mpc-ink);letter-spacing:-.03em;margin:.58rem 0 0;font-size:clamp(1.18rem,2.5vw,1.52rem);font-weight:720;line-height:1.12}.MpcPathwayExplorer-module__EJMKZq__activeExplanation>p{color:var(--mpc-muted);margin:.85rem 0 0;font-size:.78rem;line-height:1.62}.MpcPathwayExplorer-module__EJMKZq__activeExplanation ul{gap:.58rem;margin:1rem 0 0;padding:0;list-style:none;display:grid}.MpcPathwayExplorer-module__EJMKZq__activeExplanation li{color:var(--mpc-ink-soft);gap:.5rem;font-size:.7rem;line-height:1.48;display:flex}.MpcPathwayExplorer-module__EJMKZq__activeExplanation li svg{width:.85rem;height:.85rem;color:var(--mpc-green);flex:none;margin-top:.15rem}.MpcPathwayExplorer-module__EJMKZq__activeBadges{margin-top:auto;padding-top:1.15rem}.MpcPathwayExplorer-module__EJMKZq__mechanismStage{background:radial-gradient(circle at 72% 42%, color-mix(in srgb, var(--mpc-blue) 9%, transparent), transparent 17rem), var(--mpc-surface);min-width:0;position:relative;overflow:hidden}.MpcPathwayExplorer-module__EJMKZq__mechanismStage svg{width:100%;height:auto;display:block}.MpcPathwayExplorer-module__EJMKZq__cellField{fill:color-mix(in srgb, var(--mpc-surface-muted) 82%, transparent);stroke:var(--mpc-line);stroke-width:1.5px}.MpcPathwayExplorer-module__EJMKZq__zoneLabel{fill:var(--mpc-faint);font-family:var(--font-geist-mono), Consolas, monospace;letter-spacing:1.7px;font-size:11px;font-weight:700}.MpcPathwayExplorer-module__EJMKZq__glycolysisNode circle,.MpcPathwayExplorer-module__EJMKZq__pyruvateNode circle,.MpcPathwayExplorer-module__EJMKZq__lactateBranch circle{fill:var(--mpc-surface);stroke:var(--mpc-line-strong);stroke-width:2px}.MpcPathwayExplorer-module__EJMKZq__glycolysisNode text,.MpcPathwayExplorer-module__EJMKZq__pyruvateNode text,.MpcPathwayExplorer-module__EJMKZq__lactateBranch text,.MpcPathwayExplorer-module__EJMKZq__mitochondrion text,.MpcPathwayExplorer-module__EJMKZq__mpcGate text,.MpcPathwayExplorer-module__EJMKZq__activationSignal text,.MpcPathwayExplorer-module__EJMKZq__stressSignal text{fill:var(--mpc-ink-soft);font-family:var(--font-geist-sans), Arial, sans-serif;text-anchor:middle;font-size:13px;font-weight:720}.MpcPathwayExplorer-module__EJMKZq__glycolysisNode text{font-size:12px}.MpcPathwayExplorer-module__EJMKZq__route{fill:none;stroke-linecap:round;stroke-width:4px;transition:opacity .24s,stroke .24s,stroke-width .24s}.MpcPathwayExplorer-module__EJMKZq__arrowHead{fill:var(--mpc-blue)}.MpcPathwayExplorer-module__EJMKZq__glycolysisRoute,.MpcPathwayExplorer-module__EJMKZq__mitoRoute,.MpcPathwayExplorer-module__EJMKZq__mitoRouteInside{stroke:var(--mpc-blue)}.MpcPathwayExplorer-module__EJMKZq__lactateRoute,.MpcPathwayExplorer-module__EJMKZq__activationRoute{stroke:var(--mpc-green)}.MpcPathwayExplorer-module__EJMKZq__stressRoute{stroke:var(--mpc-red)}.MpcPathwayExplorer-module__EJMKZq__mitochondrion>path:first-child{fill:color-mix(in srgb, var(--mpc-blue-soft) 72%, var(--mpc-surface));stroke:var(--mpc-blue);stroke-width:2px}.MpcPathwayExplorer-module__EJMKZq__crista{fill:none;stroke:color-mix(in srgb, var(--mpc-blue) 70%, var(--mpc-muted));stroke-linecap:round;stroke-width:3px}.MpcPathwayExplorer-module__EJMKZq__mpcGate rect{fill:var(--mpc-surface);stroke:var(--mpc-blue);stroke-width:3px}.MpcPathwayExplorer-module__EJMKZq__blocker{opacity:0;transition:opacity .22s}.MpcPathwayExplorer-module__EJMKZq__blocker circle{fill:var(--mpc-red-soft);stroke:var(--mpc-red);stroke-width:3px}.MpcPathwayExplorer-module__EJMKZq__blocker path{fill:none;stroke:var(--mpc-red);stroke-linecap:round;stroke-width:4px}.MpcPathwayExplorer-module__EJMKZq__lactateBranch,.MpcPathwayExplorer-module__EJMKZq__activationSignal,.MpcPathwayExplorer-module__EJMKZq__stressSignal{opacity:.16;transition:opacity .24s}.MpcPathwayExplorer-module__EJMKZq__activationSignal rect{fill:var(--mpc-green-soft);stroke:var(--mpc-green);stroke-width:2px}.MpcPathwayExplorer-module__EJMKZq__stressSignal rect{fill:var(--mpc-red-soft);stroke:var(--mpc-red);stroke-width:2px}.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=acute] .MpcPathwayExplorer-module__EJMKZq__blocker,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=stress] .MpcPathwayExplorer-module__EJMKZq__blocker{opacity:1}.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=acute] .MpcPathwayExplorer-module__EJMKZq__mitoRoute,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=acute] .MpcPathwayExplorer-module__EJMKZq__mitoRouteInside,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=stress] .MpcPathwayExplorer-module__EJMKZq__mitoRoute,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=stress] .MpcPathwayExplorer-module__EJMKZq__mitoRouteInside{opacity:.18}.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=acute] .MpcPathwayExplorer-module__EJMKZq__lactateBranch,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=acute] .MpcPathwayExplorer-module__EJMKZq__activationSignal,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=stress] .MpcPathwayExplorer-module__EJMKZq__lactateBranch,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=stress] .MpcPathwayExplorer-module__EJMKZq__stressSignal{opacity:1}.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-view=stress] .MpcPathwayExplorer-module__EJMKZq__activationSignal{opacity:.3}.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-playing=true] .MpcPathwayExplorer-module__EJMKZq__glycolysisRoute,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-playing=true] .MpcPathwayExplorer-module__EJMKZq__mitoRoute,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-playing=true] .MpcPathwayExplorer-module__EJMKZq__mitoRouteInside,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-playing=true] .MpcPathwayExplorer-module__EJMKZq__lactateRoute,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-playing=true] .MpcPathwayExplorer-module__EJMKZq__activationRoute,.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-playing=true] .MpcPathwayExplorer-module__EJMKZq__stressRoute{stroke-dasharray:10 8;animation:1.25s linear infinite MpcPathwayExplorer-module__EJMKZq__routeFlow}.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-playing=true][data-view=acute] .MpcPathwayExplorer-module__EJMKZq__activationSignal{animation:2.2s ease-in-out infinite MpcPathwayExplorer-module__EJMKZq__activationPulse}.MpcPathwayExplorer-module__EJMKZq__mechanismStage[data-playing=true][data-view=stress] .MpcPathwayExplorer-module__EJMKZq__stressSignal{animation:1.9s ease-in-out infinite MpcPathwayExplorer-module__EJMKZq__stressPulse}.MpcPathwayExplorer-module__EJMKZq__stageKey{border-top:1px solid var(--mpc-line);color:var(--mpc-faint);background:var(--mpc-surface-muted);flex-wrap:wrap;gap:.45rem .85rem;padding:.72rem .9rem;font-size:.58rem;font-weight:680;display:flex}.MpcPathwayExplorer-module__EJMKZq__stageKey span{align-items:center;gap:.3rem;display:inline-flex}.MpcPathwayExplorer-module__EJMKZq__stageKey i{background:var(--mpc-blue);border-radius:999px;width:.5rem;height:.5rem;display:block}.MpcPathwayExplorer-module__EJMKZq__stageKey i[data-tone=proposed]{background:var(--mpc-green)}.MpcPathwayExplorer-module__EJMKZq__stageKey i[data-tone=stress]{background:var(--mpc-red)}.MpcPathwayExplorer-module__EJMKZq__comparison{border-top:1px solid var(--mpc-line);background:color-mix(in srgb, var(--mpc-surface-muted) 54%, transparent);padding:clamp(1.6rem,5vw,3rem) clamp(1.25rem,4vw,2.5rem)}.MpcPathwayExplorer-module__EJMKZq__comparisonHeading{margin-bottom:1.4rem}.MpcPathwayExplorer-module__EJMKZq__comparisonHeading h3{font-size:clamp(1.45rem,3vw,2.15rem)}.MpcPathwayExplorer-module__EJMKZq__tableWrap{border:1px solid var(--mpc-line-strong);background:var(--mpc-surface);border-radius:1rem;overflow-x:auto}.MpcPathwayExplorer-module__EJMKZq__table{border-collapse:collapse;width:100%;min-width:45rem;color:var(--mpc-ink-soft);font-size:.68rem;line-height:1.48}.MpcPathwayExplorer-module__EJMKZq__table th,.MpcPathwayExplorer-module__EJMKZq__table td{border-right:1px solid var(--mpc-line);border-bottom:1px solid var(--mpc-line);text-align:left;vertical-align:top;padding:.9rem .85rem}.MpcPathwayExplorer-module__EJMKZq__table tr:last-child th,.MpcPathwayExplorer-module__EJMKZq__table tr:last-child td{border-bottom:0}.MpcPathwayExplorer-module__EJMKZq__table th:last-child,.MpcPathwayExplorer-module__EJMKZq__table td:last-child{border-right:0}.MpcPathwayExplorer-module__EJMKZq__table thead th{color:var(--mpc-muted);background:var(--mpc-surface-muted);font-family:var(--font-geist-mono), Consolas, monospace;letter-spacing:.06em;text-transform:uppercase;font-size:.57rem;font-weight:760}.MpcPathwayExplorer-module__EJMKZq__table tbody th{width:8.2rem;color:var(--mpc-ink)}.MpcPathwayExplorer-module__EJMKZq__table tbody th strong,.MpcPathwayExplorer-module__EJMKZq__table tbody th span{display:block}.MpcPathwayExplorer-module__EJMKZq__table tbody th strong{font-size:.83rem}.MpcPathwayExplorer-module__EJMKZq__table tbody th span,.MpcPathwayExplorer-module__EJMKZq__table td small{color:var(--mpc-faint);margin-top:.2rem;font-size:.58rem;font-weight:600}.MpcPathwayExplorer-module__EJMKZq__table td p{margin:0}.MpcPathwayExplorer-module__EJMKZq__table td>strong{color:var(--mpc-ink)}.MpcPathwayExplorer-module__EJMKZq__tableBadges{margin-top:.65rem}.MpcPathwayExplorer-module__EJMKZq__programCards{gap:.75rem;display:none}.MpcPathwayExplorer-module__EJMKZq__programCard{border:1px solid var(--mpc-line-strong);background:var(--mpc-surface);border-radius:.95rem;overflow:hidden}.MpcPathwayExplorer-module__EJMKZq__programCard header{border-bottom:1px solid var(--mpc-line);background:var(--mpc-surface-muted);justify-content:space-between;align-items:flex-start;gap:.75rem;padding:.95rem 1rem;display:flex}.MpcPathwayExplorer-module__EJMKZq__programCard header span{color:var(--mpc-faint);font-size:.58rem;font-weight:680;display:block}.MpcPathwayExplorer-module__EJMKZq__programCard h4{color:var(--mpc-ink);margin:.2rem 0 0;font-size:1rem}.MpcPathwayExplorer-module__EJMKZq__programCard header>strong{color:var(--mpc-blue);flex:none;font-size:.66rem}.MpcPathwayExplorer-module__EJMKZq__programCard dl{gap:0;margin:0;display:grid}.MpcPathwayExplorer-module__EJMKZq__programCard dl>div{border-bottom:1px solid var(--mpc-line);grid-template-columns:5.2rem minmax(0,1fr);gap:.7rem;padding:.72rem 1rem;display:grid}.MpcPathwayExplorer-module__EJMKZq__programCard dt{color:var(--mpc-faint);font-family:var(--font-geist-mono), Consolas, monospace;letter-spacing:.04em;text-transform:uppercase;font-size:.56rem;font-weight:760}.MpcPathwayExplorer-module__EJMKZq__programCard dd{color:var(--mpc-ink-soft);margin:0;font-size:.68rem;line-height:1.52}.MpcPathwayExplorer-module__EJMKZq__cardBadges{padding:.75rem 1rem}.MpcPathwayExplorer-module__EJMKZq__bottomLine{border-top:1px solid var(--mpc-line-strong);background:var(--mpc-ink);grid-template-columns:auto minmax(0,1fr);align-items:start;gap:.9rem;padding:1.2rem clamp(1.25rem,4vw,2.5rem);display:grid}.MpcPathwayExplorer-module__EJMKZq__bottomLine>span{border:1px solid color-mix(in srgb, var(--mpc-surface) 30%, transparent);width:2.15rem;height:2.15rem;color:var(--mpc-surface);font-family:var(--font-geist-mono), Consolas, monospace;border-radius:999px;place-items:center;font-size:.62rem;display:grid}.MpcPathwayExplorer-module__EJMKZq__bottomLine strong{color:var(--mpc-surface);font-size:.73rem}.MpcPathwayExplorer-module__EJMKZq__bottomLine p{max-width:47rem;color:color-mix(in srgb, var(--mpc-surface) 73%, transparent);margin:.28rem 0 0;font-size:.7rem;line-height:1.55}@keyframes MpcPathwayExplorer-module__EJMKZq__routeFlow{to{stroke-dashoffset:-36px}}@keyframes MpcPathwayExplorer-module__EJMKZq__activationPulse{0%,to{opacity:.72}50%{opacity:1}}@keyframes MpcPathwayExplorer-module__EJMKZq__stressPulse{0%,to{opacity:.65}50%{opacity:1}}@media (max-width:900px){.MpcPathwayExplorer-module__EJMKZq__header{grid-template-columns:1fr}.MpcPathwayExplorer-module__EJMKZq__legend{justify-content:flex-start}.MpcPathwayExplorer-module__EJMKZq__pathwayPanel{grid-template-columns:1fr}.MpcPathwayExplorer-module__EJMKZq__mechanismStage{order:-1}.MpcPathwayExplorer-module__EJMKZq__activeBadges{margin-top:1rem}.MpcPathwayExplorer-module__EJMKZq__tableWrap{display:none}.MpcPathwayExplorer-module__EJMKZq__programCards{display:grid}}@media (max-width:580px){.MpcPathwayExplorer-module__EJMKZq__root{border-radius:1rem;margin-inline:-.25rem}.MpcPathwayExplorer-module__EJMKZq__toolbar{flex-direction:column;align-items:flex-start}.MpcPathwayExplorer-module__EJMKZq__motionControls{justify-content:stretch;width:100%}.MpcPathwayExplorer-module__EJMKZq__motionControls button{flex:1;min-height:2.75rem}.MpcPathwayExplorer-module__EJMKZq__tabs{min-width:30rem}.MpcPathwayExplorer-module__EJMKZq__mechanismStage svg{min-width:33rem;transform:translate(-1.8rem)}.MpcPathwayExplorer-module__EJMKZq__mechanismStage{overflow-x:auto}.MpcPathwayExplorer-module__EJMKZq__programCard dl>div{grid-template-columns:1fr;gap:.3rem}.MpcPathwayExplorer-module__EJMKZq__bottomLine{grid-template-columns:1fr}}@media (prefers-reduced-motion:reduce){.MpcPathwayExplorer-module__EJMKZq__root *,.MpcPathwayExplorer-module__EJMKZq__root :before,.MpcPathwayExplorer-module__EJMKZq__root :after{scroll-behavior:auto!important;transition-duration:.001ms!important;animation-duration:.001ms!important;animation-iteration-count:1!important}.MpcPathwayExplorer-module__EJMKZq__motionControls button:hover:not(:disabled){transform:none}}
